《植物生理学报》 2018, 54(5): 702-708

拟南芥PRC1蛋白功能研究进展

丰景¹, 卢江^1,2,*

¹广西农业科学院, 广西作物遗传改良生物技术重点开放实验室, 南宁530007; ²上海交通大学农业与生物学院, 上海200024

通信作者：卢江；E-mail: jiang.lu@sjtu.edu.cn

摘　要：

多梳家族蛋白(PcG)是一类高度保守的表观调控因子, 在动植物中普遍存在, 发挥着重要的生物学功能。PcG蛋白形成多个蛋白复合物, 如Polycomb repressive complex 1 (PRC1)和PRC2, 其作用是抑制基因的表达。PRC2组分在植物中保守并且已经在拟南芥中被广泛研究。相比之下, PRC1的组成和功能在动植物之间存在较大差异。本文对拟南芥PRC1蛋白的特异性和保守性进行了综述, 并强调了拟南芥PRC1组分在种子胚发育、种子萌发、茎尖干细胞命运确定和花发育中的关键作用。

关键词：表观调控; Polycomb group; H3K27me3; PRC2; PRC1

收稿：2018-03-12   修定：2018-04-23

资助：广西自然科学基金(2016GXNSFCA380020)、中国博士后科学基金(2017M613268XB)和广西农业科学院博士后基金(桂农科博2016025)。

Advances in PRC1 protein functions in Arabidopsis thaliana

FENG Jing¹, LU Jiang^1,2,*

¹Guangxi Crop Genetic Improvement and Biotechnology Laboratory, Guangxi Academy of Agricultural Sciences, Nanning 530007, China; ²School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai 200024, China

Corresponding author: LU Jiang; E-mail: jiang.lu@sjtu.edu.cn

Abstract:

Polycomb group (PcG) is a highly conserved epigenetic regulator that is ubiquitous in plants and animals and plays an important biological role. PcG proteins form multiple protein complexes, e.g. Polycomb repressive complex 1 (PRC1) and PRC2, which repress the expression of thousands of genes. PRC2 components are conserved in plants and have been extensively characterized in Arabidopsis thaliana. In contrast, PRC1 composition and function are more diverged between animals and plants. Here we review the aspects of A. thaliana-specific and -conserved PRC1 and highlight critical roles of PRC1 components in seed embryonic trait determinacy, seed germination, shoot stem cell fate determinacy and flower development in A. thaliana.

Key words: epigenetic regulation; Polycomb group; H3K27me3; PRC2; PRC1